A 38-year-old woman with a history of mitral valve prolapse attends the surgery upon advice of her dentist. She is due to have a dental filling next week and has been told to ask about prophylactic antibiotics for this procedure. What is the SINGLE MOST appropriate course of action for this patient?

1. Reassure that prophylactic antibiotics are not required

2. Prescribe amoxicillin

3. Prescribe cefalexin

4. Prescribe erythromycin

5. Prescribe phenoxymethylpenicillin (penicillin V)

Antibiotic prophylaxis against infective endocarditis is not recommended routinely for people undergoing dental procedures.

Reference

• Prophylaxis against Infective Endocarditis: antimicrobial prophylaxis against infective endocarditis in adults and children undergoing interventional procedures (NICE CG 64, 2016, updated)